The ProblemA 32-year-old woman with a history of fibromyalgia and irritable bowel syndrome presents to you for evaluation of rectal pain of 3 weeks’ duration. She has had episodes of diarrhea alternating with constipation for years. Despite psyllium therapy, her stools have been hard and difficult to pass. During defecation 3 weeks ago, she developed excruciating pain that lasted for 60 minutes. Presently, she says it feels like she is passing “broken glass” with every bowel movement. She has...

The 19th to 22nd of September 2010 marked the celebration of Asian Pacific Digestion Week (APDW) 2010, hosted by the Malaysian Society of Gastroenterology and Hepatology and held at the Kuala Lumpur Convention Centre, Malaysia. Jose Manguiat reports on two state-of-the-art lectures. The Woody Allen, Einstein assessment of neuroendocrine tumours: Puns, peptides, and polonium Acid secretion: Now too much of a good thing in the developed world? The Woody Allen, Einstein...